Recurrent Preganancy Loss

• First trimester recurrent miscarriage (> 2 losses prior to 12 weeks)
• Fetal demise (in utero death) in the second and third trimesters
• Known existence of acquired and/or genetic thrombophilia (clotting disorder)
• Family history of clotting disorders and pregnancy loss
• Incompetent CervixCervix:
  The lower part of the uterus extending from the isthmus of the uterus into the vagina.  related loss
  • Loss with premature rupture of membranes
  • Loss with vaginal bleeding with or without pain
  • Previous CerclageCerclage:
    The placement of a nonabsorbable suture around a functionally incompetent uterine cervix.  (cervical stitch) failure
  • Patients with short CervixCervix:
    The lower part of the uterus extending from the isthmus of the uterus into the vagina.  from prior surgery
  • Patients with history of LEEP procedure for cervical HPV disease
• PretermPreterm:
  Occuring or appearing before the expected time at the end of a full-term pregnancy.  labor related loss
• History of premature rupture of membranes between 24 and 37 weeks gestation
• History of a previous child with deficient IntrauterineIntrauterine:
  Occurring or situated within the uterus.  growth (IUGR/ Small for dates NeonateNeonate:
  A newborn infant, especially one less than four weeks old. )
  • Patients with a previous child with cerebral palsy
  • Patients with a previous pregnancy complicated by PretermPreterm:
    Occuring or appearing before the expected time at the end of a full-term pregnancy.  labor and/or PretermPreterm:
    Occuring or appearing before the expected time at the end of a full-term pregnancy.  delivery.
  • Management of pregnancy in patients with history of infertility prior to current pregnancy (patients with history of infertility are at significantly higher risk for fetal growth failure, fetal loss and premature delivery during the current pregnancy regardless of the number of fetuses they carry).
  • Pregnancies complicated by uterine anomalies and leiomyomata (fibroid tumors)