Recurrent Preganancy Loss

• First trimester recurrent miscarriage (> 2 losses prior to 12 weeks)
• Fetal demise (in utero death) in the second and third trimesters
• Known existence of acquired and/or genetic thrombophilia (clotting disorder)
• Family history of clotting disorders and pregnancy loss
• Incompetent cervix related loss
  • Loss with premature rupture of membranes
  • Loss with vaginal bleeding with or without pain
  • Previous cerclage (cervical stitch) failure
  • Patients with short cervix from prior surgery
  • Patients with history of LEEP procedure for cervical HPV disease
• Preterm labor related loss
• History of premature rupture of membranes between 24 and 37 weeks gestation
• History of a previous child with deficient intrauterine growth (IUGR/ Small for dates neonate)
  • Patients with a previous child with cerebral palsy
  • Patients with a previous pregnancy complicated by preterm labor and/or preterm delivery.
  • Management of pregnancy in patients with history of infertility prior to current pregnancy (patients with history of infertility are at significantly higher risk for fetal growth failure, fetal loss and premature delivery during the current pregnancy regardless of the number of fetuses they carry).
  • Pregnancies complicated by uterine anomalies and leiomyomata (fibroid tumors)