Why is thrombophilia especially dangerous in pregnancy?

Alexander Kofinas M.D.

There are two reasons that thrombophilia is particularly dangerous to pregnant women. First, the pregnant woman is more likely to form clots in her body because pregnancy increases the general risk for clot formation. In women with thrombophilia this risk is magnified many times over. Second, pregnancy outcomes are dependent on a healthy placenta, and in women with thrombophilia the ...

Are there different types of thrombophilia?

Alexander Kofinas M.D.

There are two types of thrombophilia: genetic and acquired. A defective gene from our parents usually transmits genetic thrombophilia. Occasionally, the gene defect (mutation) that causes thrombophilia may appear for the first time in a child whose parents do not carry the gene (de novo mutation). Acquired thrombophilia is the result of an immune system malfunction, which causes the production ...

What is Thrombophilia?

Alexander Kofinas M.D.

Thrombophilia is a combination of two Greek words. The word "thrombos" means clot, and the word "philia" means friendship. In short, thrombophilia is a condition, which increases the body's tendency to form blood clots.

How common is thrombophilia?

Alexander Kofinas M.D.

In the United States alone, 2 million people die every year because of this condition. To put this in perspective, all cancers in the US combined kill only 500,000 people per year. However, looking at the death toll can be deceiving since many people who suffer from strokes or other blood clotting episodes may survive but remain disabled. Overall, 30-50% ...