Pregnancy loss in the third trimester may be the result of an accident, such as an umbilical cord compression, which may be caused for a variety of reasons. Such accidents can only rarely be prevented. Most of the fetal losses in the second and third trimester are due to placental failure, and as such are preventable as long as the cause of fetal death can be identified. Careful history and pathologic examination of the placenta along with fetal autopsy can identify more than 80% of the causes and thus help us manage the next pregnancy safely. At KOFINAS PERINATAL, we have been able to help a large number of patients take home a healthy baby despite having suffered a previous loss.