About 60% of our blood is water, meaning that it must remain in a liquid state at all times for as long as our vascular system is intact and to clot only at times of injury in order to protect us from excess bleeding. In patients with thrombophilia the blood inside an intact vessel forms a clot (thrombus), which blocks the free flow of blood. This leads to an obstruction of the vessels, much like a damn obstructs the flow of water in a river, only in this case we want the river to flow naturally without any sort of obstacles. If the river of blood slows down its movement or ceases to flow entirely, then subsequent damage of the body's organic tissues can occur since blood flow is the means by which our body provides itself with oxygen. This is the cause of conditions such as, DVT (clots in the veins of the legs), stroke (clot in any brain vessel), heart attack (blockage of the heart vessels), arterial thrombosis of various organs (liver, kidneys, intestine, etc.). In short, the answer is most certainly yes.
